Monte Rosa Therapeutics is seeking an experienced Senior Accountant to play a key role in the Company’s SEC reporting, audit management, and SOX 404(b) implementation. This position will also support income tax provision activities and month-end close procedures. The ideal candidate will bring strong public company reporting experience, attention to detail, and the ability to thrive in a dynamic biotech environment.

The Director , New Product Planning will play a strategic leadership role in shaping the commercial success of Monte Rosa’s emerging pipeline. This individual will direct global commercial assessments, forecast development, and go-to-market planning for new therapeutic candidates. A critical component of this role involves driving early market access strategy to ensure optimal pricing and reimbursement potential.  The individual should have deep expertise in market analysis, forecasting, global pricing and market access, and cross-functional collaboration to inform investment decisions and help guide clinical and commercial planning.

The Director, Contracts Management must thrive in a dynamic, high-performing and collaborative environment, demonstrating a proven ability to work cross-functionally as a trusted, solutions-oriented business partner. The role will broadly support Monte Rosa Therapeutics’ (“MRTx”) global contracting function and requires substantial experience in drafting, reviewing and negotiating a wide range of agreements spanning research and development, clinical development, business development and general and administrative matters. 

Monte Rosa Therapeutics (MRT) seeks to recruit an Associate Director/ Director Drug Product CMC to play a key role in advancing our drug product development programs from early-stage development through commercialization. The successful candidate will join the CMC group supporting Monte Rosa’s portfolio  of molecular glue degraders (MGDs) that eliminate disease-causing proteins previously thought undruggable.   The Associate Director/ Director drug product (DP) will lead technical development activities related to...

Monte Rosa Therapeutics is seeking to recruit a highly motivated research associateto join its Proteomics group in Boston to support hit confirmation and drug target validation. This is an exciting opportunity to join a team responsible for identification and validation of novel molecular glue degrader targets. The lab-based position will focus on

We are seeking a highly motivated, creative Computational Medicinal Chemist to support drug discovery programs. The successful candidate will operate at the interface of computational chemistry and medicinal chemistry, serving as an embedded, project-facing contributor within lead identification and lead optimisation (LI/LO) teams. The position will also involve contributions to earlier drug discovery phases and the development of computational tools with direct application in medicinal chemistry. This role is strongly project-driven: you will apply computational approaches to directly...

The Associate Director of Global Office Operations is responsible for overseeing the efficient operation of company offices globally and managing the performance and coordination of the Executive Assistant (EA) and office operations team. This role ensures standardized, high-functioning office operations and consistent, strategic support for senior leadership across all sites. The ideal candidate brings a blend of operational expertise, people management skills, and strategic insight to support executive effectiveness and operational excellence

Monte Rosa Therapeutics is searching for a Sr Research Associate - In Vivo to assist in executing pivotal proof-of-concept studies in pre-clinical models in mice of inflammation, immunology, and oncology, and assist in the cross-functional development of our research strategy. The role involves interacting with team members to design and execute in vivo/ex vivo pharmacology studies aimed at defining the activity and mechanism of action of compounds. This person will work primarily in our Animal Care Facility, ideally 10am-6pm, to oversee and perform afternoon/evening and weekend dosing of animals as part of study...

Monte Rosa Therapeutics is seeking a Director Quality GCP to provide strategic oversight of phase-appropriate  Quality GCP and GCLP activities, including GCP quality oversight of ongoing quality activities supporting active pre-clinical and clinical programs through participation on in-house and external cross-functional teams.  This role requires an 75% on-site presence. You will work closely with industry leaders in Boston and Basel . Join a diverse, collaborative, and dynamic team that values innovation, teamwork, and a people-centric culture!

Monte Rosa Therapeutics is seeking an experienced and strategic Director of Regulatory Affairs to lead and support global regulatory efforts across our development programs, with a focus on immunology. The ideal candidate will be responsible for developing and executing regulatory strategies that support global product development and registration. This role requires strong regulatory knowledge, leadership skills, and the ability to work effectively in a cross-functional environment. Global regulatory experience is required, and immunology background is preferred. CMC experience is a plus.

Monte Rosa Therapeutics. looking for a Director Quality GMP with quality expertise to support all GMP/GDP quality aspects of externally produced supply of drug substance and drug product for novel molecular glue degrader (MGD) programs, making a difference for our patients every day. Responsible for oversight of phase-appropriate Monte Rosa Quality GMP and GDP activities. These activities include; cGMP quality oversight of ongoing manufacturing, testing and distribution activities supporting active pre-clinical and clinical programs through participation on in-house and external cross-functional teams. The right candidate...