The FP&A lead within the Finance team is responsible for driving strategic financial planning and analysis across a dynamic biotechnology organization. Partnering with leadership and cross-functional teams, the FP&A lead will oversee budgeting, forecasting,  management reporting, ad hoc support and strategic decision support. The role is highly visible, serving as a principal financial advisor to R&D and G&A functions while helping to shape financial strategy, optimize resource allocation and ensure alignment with organization goals in a rapidly growing clinical phase biotech.

Monte Rosa Therapeutics is searching for a Toxicology Lead to direct nonclinical safety and toxicology work for programs to enable drug candidates from discovery through development. This position will lead and develop nonclinical toxicology strategies to support Monte Rosa’s diverse drug candidates during all phases of development. The Toxicology Lead will contribute to the R&D strategy and implement the strategy and will report to the Senior Director of Nonclinical Development. This is an individual contributor role by designing, conducting or overseeing studies, analyze/interpret, and report in vitro, ex vivo, and in vivo non-GLP (or GLP...

Monte Rosa Therapeutics (MRT) seeks to recruit an enthusiastic, creative and highly talented medicinal chemist who is eager to discover molecular glue degraders (MGDs) that eliminate disease-causing proteins previously thought undruggable. This position plays a key role in contributing to the development of our growing portfolio and will have a crucial impact at the forefront of drug discovery. The successful candidate should have strong interest in early-stage drug discovery, prior experience in HTS data analysis, hit follow-up as well as utilizing state-of-the-art medicinal...

Monte Rosa Therapeutics is seeking a highly skilled and motivatedCompound Manager to join our team. You’ll play a pivotal role within our Compound Management Team, working closely with colleagues to deliver compounds in a variety of formats for the Screening Teams. Your expertise will directly support the characterization of innovative small molecule glue-based degraders and drive the advancement of our expanding pipeline. If you’re passionate about collaboration, innovation, and making a real impact in scientific discovery, we’d love to meet you.

The Director Clinical Scientist is an important and visible member of the Clinical Development team, working collaboratively with the Clinical operations lead and medical director. The Director Clinical Scientist will be responsible for scientific oversight, data integrity and quality of clinical trial(s) in support of the development strategy for programs within the Early- stage portfolio. The role is the primary contact for internal and external stakeholders for clinical aspects of the protocol, supporting strategic development, providing final recommendations to senior management.

Monte Rosa Therapeutics is seeking a  Senior Medical Writer to work directly with Clinical Operations, Clinical Research and Drug Safety groups on  various clinical and nonclinical regulatory documents ( e.g. study protocols, Investigator Brochures, Clinical Study Reports, Annual Reports, INDs, and NDAs) as well as clinical and nonclinical publications (e.g. abstracts, posters, and manuscripts). This position will assume lead writing responsibility on up to 5 clinical studies potentially leading to an NDA, including both regulatory and publication documentation. This position will also lead writing assignments on other programs in early development.  

The Director of Drug Safety & Pharmacovigilance provides strategic and hands‑on leadership for pharmacovigilance activities supporting a clinical‑stage biotech pipeline in inflammatory and oncology diseases. This role is responsible for establishing and executing global safety strategy across early‑ and mid‑stage clinical programs, with particular focus on immune‑mediated toxicities, oncology risk management, and complex benefit–risk assessment. The Director partners closely with Clinical Development and Regulatory teams to integrate safety...

The Director of Biostatistics is a hands‑on statistical leader responsible for the design, analysis, and interpretation of Phase 1–Phase 3 clinical trials with a primary focus on inflammation and oncology indications. This role combines scientific leadership with active execution and intensive CRO oversight, ensuring high‑quality statistical deliverables across outsourced clinical studies. The Director will work closely with Clinical Development and external partners to drive trial design, analysis strategies, and...

Monte Rosa Therapeutics is seeking passionate Intern in Synthetic Chemistry for 6 months to help us to eliminate disease causing proteins through targeted protein degradation - a novel and exciting way of drugging un-druggable proteins. You will work with an industry leader who will direct and mentor you on your project, bridging the medicinal chemistry team and the chemistry CRO in the design of synthetic chemistry routes of biological relevant compounds. You will join a diverse, thoughtful, fun and collaborative environment that emphasizes teamwork and putting people first!

Monte Rosa is seeking a Program Management Solutions lead to support and enhance program management capabilities across the organization. This role will partner closely with Program Management and key stakeholders to assess needs, implement tools, and standardize reporting to improve visibility, efficiency, and decision-making.

Monte Rosa Therapeutics is seeking passionate Intern Research Associates for 6 months to help us to eliminate disease causing proteins through targeted protein degradation ­­­– a novel and exciting approach to drugging proteins that until recently were considered un-druggable.  The candidates will gain hands-on experience within an early-stage drug discovery environment. You will work with an industry leader who will direct and mentor you on your project, expose you to other drug discovery projects, and involve you in the process of solving complex biological questions.  You will be joining a diverse, thoughtful, fun and collaborative environment that...

We are looking for a highly motivated and skilled accounting professional to be part of a growing finance team. This role will be responsible for ensuring the completeness, accuracy, and timeliness of clinical trial accruals, partnering closely with Clinical Operations, Development, and external CROs. Responsibilities will also include month-end close process and reporting, reviewing payroll, account reconciliations, fluctuation analysis, and audit support. This role will partner with the Controller, Swiss Accounting Manager, and cross-functional leaders to drive continuous improvement in financial operations. This is an opportunity for a resourceful finance leader to maintain and enhance processes and internal controls to support a high-growth innovative...

Monte Rosa Therapeutics is seeking for an experienced, energetic, and self-motivated scientist to join our BioMarker Group in Basel. Monte Rosa’s rational approach to targeting disease-causing proteins for degradation will deliver pioneering therapies for Immunology & Inflammation (I&I), oncology and other disease areas. The candidate will conduct well-designed and reliably executed experiments in the lab that are aimed at assessing preclinical, translational and clinical samples. In addition, support to internal sample management team is expected. The scientist

Monte Rosa Therapeutics seeks an experienced and highly motivated scientist to join our Biomarker and Translation team in Boston. Using a rational approach to targeted protein degradation, Monte Rosa is developing pioneering therapies across Immunology & Inflammation, Oncology, and other disease areas. The scientist in this role will be responsible for designing and executing robust translational experiments in clinically relevant models to support indication selection and patient stratification. He/she will work collaboratively with project and clinical teams to interpret emerging clinical data and inform the discovery and translation of next-generation therapeutics. Key responsibilities...

Monte Rosa Therapeutics (MRT) seeks to recruit an enthusiastic, creative and highly talented medicinal chemist who is eager to discover molecular glue degraders (MGDs) that eliminate disease-causing proteins previously thought undruggable. This position plays a key role in advancing our drug discovery projects from Lead Identification through development candidate nomination and beyond, while also enhancing the MRT degradation platform. The successful candidate should have state-of the-art medicinal chemistry expertise in small molecule drug discovery, prior experience collaborating...

The Director , New Product Planning will play a strategic leadership role in shaping the commercial success of Monte Rosa’s emerging pipeline. This individual will direct global commercial assessments, forecast development, and go-to-market planning for new therapeutic candidates. A critical component of this role involves driving early market access strategy to ensure optimal pricing and reimbursement potential.  The individual should have deep expertise in market analysis, forecasting, global pricing and market access, and cross-functional collaboration to inform investment decisions and help guide clinical and commercial planning.

The Director, Contracts Management must thrive in a dynamic, high-performing and collaborative environment, demonstrating a proven ability to work cross-functionally as a trusted, solutions-oriented business partner. The role will broadly support Monte Rosa Therapeutics’ (“MRTx”) global contracting function and requires substantial experience in drafting, reviewing and negotiating a wide range of agreements spanning research and development, clinical development, business development and general and administrative matters. 

Monte Rosa Therapeutics (MRT) seeks to recruit an Associate Director/ Director Drug Product CMC to play a key role in advancing our drug product development programs from early-stage development through commercialization. The successful candidate will join the CMC group supporting Monte Rosa’s portfolio  of molecular glue degraders (MGDs) that eliminate disease-causing proteins previously thought undruggable.   The Associate Director/ Director drug product (DP) will lead technical development activities related to...

The Associate Director of Global Office Operations is responsible for overseeing the efficient operation of company offices globally and managing the performance and coordination of the Executive Assistant (EA) and office operations team. This role ensures standardized, high-functioning office operations and consistent, strategic support for senior leadership across all sites. The ideal candidate brings a blend of operational expertise, people management skills, and strategic insight to support executive effectiveness and operational excellence

Monte Rosa Therapeutics is seeking an experienced and strategic Director of Regulatory Affairs to lead and support global regulatory efforts across our development programs, with a focus on immunology. The ideal candidate will be responsible for developing and executing regulatory strategies that support global product development and registration. This role requires strong regulatory knowledge, leadership skills, and the ability to work effectively in a cross-functional environment. Global regulatory experience is required, and immunology background is preferred. CMC experience is a plus.