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At Monte Rosa Therapeutics, we’re excited to seek a dedicated Compound Manager to join our team. You’ll play a pivotal role within our Compound Management Team, working closely with colleagues to deliver compounds in a variety of formats for the Screening Teams. Your expertise will directly support the characterization of innovative small molecule glue-based degraders and drive the advancement of our expanding pipeline. If you’re passionate about collaboration, innovation, and making a real impact in scientific discovery, we’d love to meet you.
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We are seeking a hands-on, versatile Technology Specialist — a true "jack of all trades" combining end-user computing, systems administration, and network support with a forward-looking mandate: helping our scientists and G&A teams work smarter through automation, AI-enabled tooling, and thoughtful use of our technology stack. The ideal candidate is a proactive problem-solver who takes initiative, moves fluidly between a support ticket, a patch cycle, and a workflow-automation experiment in the same day, and is genuinely excited about the potential of AI and agentic tools to reduce toil across the organization.
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Monte Rosa Therapeutics is seeking a Director Quality GCP to provide strategic oversight of phase-appropriate Quality GCP and GCLP activities, including GCP quality oversight of ongoing quality activities supporting active pre-clinical and clinical programs through participation on in-house and external cross-functional teams. This role requires an 75% on-site presence. You will work closely with industry leaders in Boston and Basel . Join a diverse, collaborative, and dynamic team that values innovation, teamwork, and a people-centric culture!
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Monte Rosa is looking for an experienced Program and Alliance Manager with research and early clinical development experience in biotech to oversee internal and partnered programs. Leveraging their drug development, project management and cross-functional team experience, the successful candidate will manage early-stage internal programs in close collaboration with program leaders, to successfully advance our pipeline. The candidate will be responsible for managing program-related activities, resolving issues, tracking progress of key milestones and budget, and achieving project goals. In addition, this individual will develop and maintain key relationships, both internally and externally, to ensure effective...
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Monte Rosa Therapeutics seeks an experienced, highly organized, and collaborative People Experience Operations (HR) Generalist to support and enhance our people operations function. This role will be responsible for managing core HR processes, systems, compliance activities, and employee lifecycle programs while helping to scale a high-performing and employee-focused global organization.
The ideal candidate thrives in a fast-paced, innovative environment and brings a continuous improvement mindset, strong analytical capabilities, and exceptional attention to detail.
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Monte Rosa Therapeutics Research Associate Contractor for 6 months to support the development and characterization of novel molecular glue degraders for the treatment of inflammatory diseases. As part of the Immunology and Preclinical Pharmacology team, this role will broadly support multiple immunology and inflammation (I&I) projects/programs from early lead optimization through clinical-stage.
The ideal candidate has a strong technical background working in I&I and a demonstrated ability to move projects/programs forward through collaborative teamwork.
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The Manager, Data Management will be responsible for overseeing clinical data management activities across one or more clinical programs. This individual will work closely with Clinical Operations, Biostats and Programming, Medical, Safety, Regulatory, external CROs, and technology vendors to ensure high-quality, inspection-ready clinical data.
This is a hands-on role well suited for someone who thrives in a small biotech environment, can...
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The Manager, GMP Quality is responsible for the oversight and day-to-day quality interface with CDMO producing DS & DP for MRTx's ongoing clinical programs.. This includes supporting the review of MBRs/EBRs, analytical methods, validation protocols/reports, specifications, release data packages and stability protocols/report. This role will also supportextneral audits , inspection readiness and regulatory authority inspections.
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We are seeking an experienced and strategically minded Associate Director, Corporate Communications to lead the execution of our external communications strategy.
The Associate Director, Corporate Communications will oversee corporate communication across press releases, investor materials, company website, social media, and components of SEC filings such as the annual report (Form 10‑K). The ideal candidate combines strong communications expertise with scientific literacy and a solid understanding of the biopharmaceutical sector, allowing this person to translate complex scientific and clinical data into clear and engaging narratives for investors, media, and other key...
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The Associate Director of Program Management will serve as a strategic and operational leader for priority immunology and inflammation programs, driving assets from mid- to late-stage development through regulatory submission. This role is designed for a hands-on, agile leader who thrives in a fast-paced biotechnology environment and can rapidly translate evolving science into executable development strategy.
As a core member of the Program Team, the Director will partner closely with Clinical, Regulatory, CMC, Nonclinical, Biomarkers, Translational Sciences, and Commercial leaders to integrate strategy and execution across the full development lifecycle. This individual will ensure alignment to the Target Product Profile (TPP) and...
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Responsible for the coordination and preparation of document packages for regulatory submissions ensuring compliance with the Food and Drug Administration (FDA) and international regulations/interpretations. May determine methods and procedures on some assignments and may provide guidance to other lower-level personnel.
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The Director of Drug Safety & Pharmacovigilance provides strategic and hands‑on leadership for pharmacovigilance activities supporting a clinical‑stage biotech pipeline in inflammatory and oncology diseases. This role is responsible for establishing and executing global safety strategy across early‑ and mid‑stage clinical programs, with particular focus on immune‑mediated toxicities, oncology risk management, and complex benefit–risk assessment. The Director partners closely with Clinical Development and Regulatory teams to integrate safety...
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The Director of Biostatistics is a hands‑on statistical leader responsible for the design, analysis, and interpretation of Phase 1–Phase 3 clinical trials with a primary focus on inflammation and oncology indications. This role combines scientific leadership with active execution and intensive CRO oversight, ensuring high‑quality statistical deliverables across outsourced clinical studies.
The Director will work closely with Clinical Development and external partners to drive trial design, analysis strategies, and...
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Monte Rosa Therapeutics is seeking an experienced and strategic Director of Regulatory Affairs to lead and support global regulatory efforts across our development programs, with a focus on immunology. The ideal candidate will be responsible for developing and executing regulatory strategies that support global product development and registration. This role requires strong regulatory knowledge, leadership skills, and the ability to work effectively in a cross-functional environment. Global regulatory experience is required, and immunology background is preferred. CMC experience is a plus.