The Associate Director of Global Office Operations is responsible for overseeing the efficient operation of company offices globally and managing the performance and coordination of the Executive Assistant (EA) and office operations team. This role ensures standardized, high-functioning office operations and consistent, strategic support for senior leadership across all sites. The ideal candidate brings a blend of operational expertise, people management skills, and strategic insight to support executive effectiveness and operational excellence

  Monte Rosa Therapeutics is seeking a Research Associate/Senior Research Associate - Biology to support early target validation in immunology and inflammation, aiding in the advancement of our molecular glue degraders into clinic. The successful candidate will collaborate with team members to design and execute in vitro experiments focused on determining the activity and mechanism of action of compounds. This role requires hands-on laboratory work, conducting a variety of in vitro experiments.

Monte Rosa Therapeutics (MRT) is a clinical-stage biotechnology company pioneering the discovery and development of molecular glue degraders (MGDs) to eliminate disease-causing proteins previously considered undruggable. We are seeking an accomplished and collaborative Senior Director of Medicinal Chemistry to lead and shape our drug discovery efforts in Boston. This leadership role will be central to advancing our growing pipeline from hit identification through development candidate nomination and IND-enabling studies. The ideal candidate will bring deep medicinal chemistry expertise, strong leadership capabilities, and a passion for driving innovative science toward transformative medicines.

Monte Rosa Therapeutics is searching for a Sr Research Associate - In Vivo to assist in executing pivotal proof-of-concept studies in pre-clinical models in mice of inflammation, immunology, and oncology, and assist in the cross-functional development of our research strategy. The role involves interacting with team members to design and execute in vivo/ex vivo pharmacology studies aimed at defining the activity and mechanism of action of compounds. This person will work primarily in our Animal Care Facility, ideally 10am-6pm, to oversee and perform afternoon/evening and weekend dosing of animals as part of study...

Monte Rosa Therapeutics is seeking a Director Quality GCP to provide strategic oversight of phase-appropriate  Quality GCP and GCLP activities, including GCP quality oversight of ongoing quality activities supporting active pre-clinical and clinical programs through participation on in-house and external cross-functional teams.  This role requires an 75% on-site presence. You will work closely with industry leaders in Boston and Basel . Join a diverse, collaborative, and dynamic team that values innovation, teamwork, and a people-centric culture!

Monte Rosa Therapeutics is seeking a passionate candidate for an internship in the Immunology and Inflammation Biology group to help us identify molecular glue degraders to eliminate disease causing proteins through targeted protein degradation ­­­– a novel and exciting field for targeting proteins that were previously considered un-druggable. The candidate will contribute to enhancing protein degradation in primary human immune cells to guide discovery and prioritization of novel targets. This internship will...

Monte Rosa Therapeutics is seeking an experienced and strategic Director of Regulatory Affairs to lead and support global regulatory efforts across our development programs, with a focus on immunology. The ideal candidate will be responsible for developing and executing regulatory strategies that support global product development and registration. This role requires strong regulatory knowledge, leadership skills, and the ability to work effectively in a cross-functional environment. Global regulatory experience is required, and immunology background is preferred. CMC experience is a plus.

Monte Rosa Therapeutics seeks to recruit a highly motivated research associate to join its proteomics group in Boston. This is an exciting opportunity to join a team responsible for target identification of novel small molecule degraders. The successful candidate will be responsible for independently conducting his/her own experiments from sample preparation, LC-MS acquisition, to data analysis, interpretation, and presentation of the proteomics results. The candidate should exhibit excellent communication and collaborative skills for working on cross-functional multi-disciplinary drug discovery teams.

Monte Rosa Therapeutics (MRT) seeks to recruit an experienced, creative and highly talented DMPK and ADME Scientist who is eager will assit in leading the discovery and development effort to grow the drug pipelines, as well as help lead external GxP compliance research efforts. The Scientist will work MRTx colleagues to participate in all stages of DMPK and ADME assessments, from initial compound screening through to IND and NDA regulatory submissions. Working with Research, Bioanalytical and Clinical Science subject matter experts, provides scientific expertise to ensure that clinical candidates with acceptable drug development characteristics are identified and appropriately characterized. Represents Preclinical Development on Research and Development teams and...

We are seeking an energetic and highly motivated individual to join our Clinical Operations team.  This position  has the opportunity to significantly contribute to the growth and development of a top-tier Biotech company. The CTA position is focused on providing support associated with the planning, start-up, maintenance, and closeout of clinical trials. The ideal candidate will be proactive and detail oriented with a desire to be involved in all aspects of clinical trial execution.

Monte Rosa Therapeutics is seeking a contractor (initial 6 months) with the experience to implement and run complex cellular assays. This position is a key role in the pivotal team responsible for Automation and Screening Technologies & hits-to-leads support for Monte Rosa’s diverse pipeline. The ideal candidate will be able to help evolve Monte Rosa’s hit identification and hits-to-leads endeavors through embracing novel assay technologies, enhancing overall processes and actively drive internal and external partnerships.

Monte Rosa Therapeutics. looking for a Director Quality GMP with quality expertise to support all GMP/GDP quality aspects of externally produced supply of drug substance and drug product for novel molecular glue degrader (MGD) programs, making a difference for our patients every day. Responsible for oversight of phase-appropriate Monte Rosa Quality GMP and GDP activities. These activities include; cGMP quality oversight of ongoing manufacturing, testing and distribution activities supporting active pre-clinical and clinical programs through participation on in-house and external cross-functional teams. The right candidate...