Monte Rosa Therapeutics is seeking an experienced Senior Accountant to play a key role in the Company’s SEC reporting, audit management, and SOX 404(b) implementation. This position will also support income tax provision activities and month-end close procedures. The ideal candidate will bring strong public company reporting experience, attention to detail, and the ability to thrive in a dynamic biotech environment.

SEC Reporting & Technical Accounting

• Prepare quarterly and annual SEC filings, including Forms 10-Q, 10-K, and related disclosures
• Prepare financial statements, footnotes, and supporting schedules in accordance with U.S. GAAP
• Support the quarterly and annual income tax provision, including tax-related financial statement disclosures, in coordination with external tax advisors
• Assist with technical accounting research and preparation of accounting position memos for complex or non-routine transactions
• Support implementation and documentation of new accounting standards and updates
• Maintain and enhance accounting policies and procedures
• Assist with disclosure for the quarterly provision for income taxes

Audit & SOX Compliance

• Serve as a liaison with external auditors for quarterly reviews and annual audits
• Coordinate audit requests, prepare supporting documentation, and resolve audit inquiries
• support the implementation of SOX 404(b), including control design, documentation, testing, and remediation
• Assist in maintaining effective internal controls over financial reporting

Month-End Close

• Participate in the monthly close process, including preparation of journal entries, account reconciliations, and variance analyses
• Ensure accurate and timely close in accordance with internal deadlines
• Collaborate cross-functionally with FP&A, Legal, Tax, and other stakeholders

• Bachelor’s degree in Accounting or Finance; CPA preferred
• 4–7+ years of relevant accounting experience
• Hands-on experience with SEC reporting in a public company environment a plus
• Strong knowledge of U.S. GAAP, financial reporting, and internal controls
• Experience with SOX 404(b) implementation or compliance strongly preferred
• Public accounting experience (Big 4 or national firm) preferred
• Life sciences or biotech industry experience a plus
• Strong organizational, analytical, and communication skills
• Ability to manage multiple priorities in a fast-paced, deadline-driven environment