Monte Rosa Therapeutics is seeking a self-motivated and enthusiastic Research Associate to support our work in inflammasome biology by establishing new cellular functional assays. Specifically, you will help develop immunological assays relevant to inflammation in the liver.

1. Culture immortalized and primary cells including macrophages for immune functional assays
2. Employ cell viability and protein functional assays as well as cytokine profiling assays to assess inflammatory pathway activity in these cell types
3. Edit primary cells using CRISPR Cas9 to develop disease models
4. Survey literature to build out knowledge of the liver immune environment
5. Analyze, interpret, and present data

• Student currently in a Junior or Senior in bachelor’s program or enrolled in a master’s degree program in Immunology or Cell / Molecular Biology
• Proficiency in written and spoken English

• Required:
  • Enthusiasm for learning about drug discovery, cell biology and associated techniques, gene editing and inflammasome biology in a rigorous and fast-paced research environment
  • Ability to learn quickly
  • Preference for working as part of a team
• Pluses but not required:
  • Specific interest in targeted protein degradation
  • Previous experience with mammalian cell culture, molecular biology techniques (e.g. Western Blot, DNA extraction, PCR, gene editing with CRISPR Cas9)
  • Experience in Immunology and Cell Biology
  • BSL2 experience