Monte Rosa Therapeutics is seeking passionate  Research Associate-Intern, Proteomics to help us to eliminate disease causing proteins through targeted protein degradation­­–a novel and exciting way of drugging proteins that until recently were considered un-druggable­. The candidates will gain hands-on experience within a particular area of interest in an early-stage drug discovery environment. You will work with an industry leader who will direct and mentor you on your project, expose you to other drug discovery projects and involve you in solving complex biological questions. You will be joining a diverse, thoughtful, fun, and collaborative environment that emphasizes teamwork and putting people first!

If you have an interest in any of the following areas noted below, we will give you hands on educational experience within a high paced Drug discovery environment.

• You will investigate the substrate ubiquitination by E3 ligases using the BioE3 assay; the BioE3 assay is a new proximity based labeling technology that allows the labeling, isolation, and identification of ubiquitinated protein substrates by Proteomics.
• You will utilize your cell culture expertise for the implementation and validation of this assay in house; you will have the opportunity to learn the Proteomics sample preparation workflow followed by LC-MS analysis.
• You will be attending and presenting your data at team and project meetings.

• Our preference is for a student currently in a Bachelor or Master degree program in Cell Biology, Biochemistry, or a life science.

• Scientific desire to learn the most advance approaches to drug discovery.
• Biochemistry and Cell Biology centric individuals should have previous documented hands-on experience with mammalian cell culture, and preferably biochemical techniques (e.g., Western Blot).
• Enjoys working in a team-based environment.